51 drugs reach their earliest generic-entry date in 2027

Jan 2027 · 5

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Vibativ telavancin hydrochloride	telavancin hydrochloride	Apotex	022110	1 Jan 2027	patent
Nucynta · 3 strengths tapentadol hydrochloride	tapentadol hydrochloride	Collegium Pharm Inc	022304	3 Jan 2027	exclusivity
Provayblue · 2 strengths methylene blue	methylene blue	Provepharm Sas	204630	8 Jan 2027	exclusivity
Striverdi Respimat olodaterol hydrochloride	olodaterol hydrochloride	Boehringer Ingelheim	203108	19 Jan 2027	patent
Nevanac nepafenac	nepafenac	Harrow Eye	021862	31 Jan 2027	patent, carve-out possible

Feb 2027 · 3

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Lexiscan regadenoson	regadenoson	Astellas	022161	2 Feb 2027	patent
Colazal balsalazide disodium	balsalazide disodium	Valeant Pharms Intl	020610	24 Feb 2027	patent
Advil Allergy Sinus chlorpheniramine maleate; ibuprofen; pseudoephedrine hydrochloride	chlorpheniramine maleate; ibuprofen; pseudoephedrine hydrochloride	Haleon Us Holdings	021441	28 Feb 2027	patent

Mar 2027 · 3

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Abilify · 6 strengths aripiprazole	aripiprazole	Otsuka	021436	2 Mar 2027	patent, carve-out possible
Duavee bazedoxifene acetate; estrogens, conjugated	bazedoxifene acetate; estrogens, conjugated	Wyeth Pharms	022247	10 Mar 2027	patent
Veletri · 2 strengths epoprostenol sodium	epoprostenol sodium	Actelion	022260	15 Mar 2027	patent

Apr 2027 · 4

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Oxtellar Xr · 3 strengths oxcarbazepine	oxcarbazepine	Supernus Pharms	202810	13 Apr 2027	patent
Clinolipid 20% olive oil; soybean oil	olive oil; soybean oil	Baxter Hlthcare Corp	204508	24 Apr 2027	exclusivity
Chloraprep With Tint · 3 strengths chlorhexidine gluconate; isopropyl alcohol	chlorhexidine gluconate; isopropyl alcohol	Becton Dickinson Co	020832	25 Apr 2027	patent
Amyvid · 2 strengths florbetapir f-18	florbetapir f-18	Avid Radiopharms Inc	202008	30 Apr 2027	patent

May 2027 · 5

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Lyrica Cr · 3 strengths pregabalin	pregabalin	Upjohn	209501	2 May 2027	patent
Rapivab peramivir	peramivir	Biocryst	206426	7 May 2027	patent, carve-out possible
Aveed testosterone undecanoate	testosterone undecanoate	Endo Operations	022219	8 May 2027	patent, carve-out possible
Janumet Xr · 3 strengths metformin hydrochloride; sitagliptin phosphate	metformin hydrochloride; sitagliptin phosphate	Msd Sub Merck	202270	24 May 2027	patent
Januvia · 3 strengths sitagliptin phosphate	sitagliptin phosphate	Msd	021995	24 May 2027	patent

Jun 2027 · 5

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Balcoltra ethinyl estradiol; levonorgestrel	ethinyl estradiol; levonorgestrel	Avion Pharms	208612	1 Jun 2027	patent
Lumigan bimatoprost	bimatoprost	Abbvie	022184	13 Jun 2027	patent
Prezista darunavir	darunavir	Janssen Prods	202895	26 Jun 2027	patent
Prezista · 4 strengths darunavir	darunavir	Janssen Prods	021976	26 Jun 2027	patent
Paragard T 380a copper	copper	Coopersurgical	018680	28 Jun 2027	exclusivity

Jul 2027 · 2

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Pristiq · 3 strengths desvenlafaxine succinate	desvenlafaxine succinate	Pf Prism Cv	021992	5 Jul 2027	patent
Halaven eribulin mesylate	eribulin mesylate	Eisai Inc	201532	8 Jul 2027	patent

Aug 2027 · 6

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Suprep Bowel Prep Kit magnesium sulfate; potassium sulfate; sodium sulfate	magnesium sulfate; potassium sulfate; sodium sulfate	Azurity	022372	5 Aug 2027	exclusivity
Lampit · 2 strengths nifurtimox	nifurtimox	Bayer Healthcare	213464	6 Aug 2027	exclusivity
Protonix Iv pantoprazole sodium	pantoprazole sodium	Wyeth Pharms	020988	12 Aug 2027	exclusivity
Vistogard uridine triacetate	uridine triacetate	Btg Intl	208159	17 Aug 2027	patent, carve-out possible
Oxycontin · 3 strengths oxycodone hydrochloride	oxycodone hydrochloride	Knoa Pharma	022272	24 Aug 2027	patent
Azilect · 2 strengths rasagiline mesylate	rasagiline mesylate	Teva	021641	27 Aug 2027	patent

Sep 2027 · 2

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Edurant rilpivirine hydrochloride	rilpivirine hydrochloride	Janssen Prods	202022	15 Sep 2027	exclusivity
Emend · 2 strengths aprepitant	aprepitant	Msd	021549	26 Sep 2027	patent

Oct 2027 · 5

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Chlorhexidine Gluconate chlorhexidine gluconate	chlorhexidine gluconate	Sage Prods	021669	2 Oct 2027	patent
Xyzal Allergy 24hr levocetirizine dihydrochloride	levocetirizine dihydrochloride	Chattem Sanofi	209090	16 Oct 2027	patent
Amitiza · 2 strengths lubiprostone	lubiprostone	Sucampo Pharma Llc	021908	25 Oct 2027	patent
Beleodaq belinostat	belinostat	Acrotech Biopharma	206256	27 Oct 2027	patent
Bronchitol mannitol	mannitol	Pharmaxis Europe	202049	30 Oct 2027	exclusivity

Nov 2027 · 1

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Acular Ls ketorolac tromethamine	ketorolac tromethamine	Abbvie	021528	24 Nov 2027	patent

Dec 2027 · 10

Drug	Ingredient	Applicant	NDA	Earliest generic entry	Basis
Toviaz · 2 strengths fesoterodine fumarate	fesoterodine fumarate	Pfizer	022030	7 Dec 2027	patent
Valcyte valganciclovir hydrochloride	valganciclovir hydrochloride	Cheplapharm	022257	11 Dec 2027	patent
Incruse Ellipta umeclidinium bromide	umeclidinium bromide	Glaxo Grp England	205382	18 Dec 2027	patent
Oracea doxycycline	doxycycline	Galderma Labs Lp	050805	19 Dec 2027	patent
Lastacaft alcaftadine	alcaftadine	Abbvie	022134	23 Dec 2027	patent, carve-out possible
Gilenya fingolimod hydrochloride	fingolimod hydrochloride	Novartis	022527	25 Dec 2027	patent, carve-out possible
Cardene In 0.83% Sodium Chloride In Plastic Container nicardipine hydrochloride	nicardipine hydrochloride	Chiesi	019734	26 Dec 2027	patent
Cardene In 0.86% Sodium Chloride In Plastic Container nicardipine hydrochloride	nicardipine hydrochloride	Chiesi	019734	26 Dec 2027	patent
Cardene In 4.8% Dextrose In Plastic Container nicardipine hydrochloride	nicardipine hydrochloride	Chiesi	019734	26 Dec 2027	patent
Tracleer bosentan	bosentan	Actelion	209279	28 Dec 2027	patent